Sunday, October 7, 2012

Types

There are 3 different types of Neurofibromatosis: Neurofibromatosis Type 1(NF1), Neurofibromatosis Type 2(NF2), and Schwannomatosis.  In diagnosing NF1, a doctor looks for changes in skin appearanc, tumors, or bone abnormalites, and/or a parent, sibling or child with NF1. It affects about 1 in every 3,000 people, ranges from mild to severe, and can cause more symptoms in some people than others. Next is NF2,  it's the less common form and may be evident to diagnose at birth and nearly always by the time the child is 10yrs old. It affects about 1 in every 25,000 people. Symptoms generally occur in the late teens and early 20's. However, some people experience symptoms in childhood and others not until age 40. Last is Schwanomatosis, which is once considered to be a variation of NF2.  It grows on the peripheral nerves throughout the body, can cause severe, debilitating pain, and neurological dysfunction. Also, it's recognized most often in people over the age of 30. 

www.hopkinsmedicine.org › ... › Neurofibromatosis Center
http://www.nfinc.org
Halder G, Johnson RL. Hippo signaling: growth control and beyond. Development. 2011;138:9–22. doi: 10.1242/dev.045500. [PMC free article] [PubMed] [Cross Ref]
 Lorenzo J, Barton B, Acosta MT, North KN. The mental motor and language development of toddlers with neurofibromatosis type 1. J Pediatr. 2011;158:660–665. doi: 10.1016/j.jpeds.2010.10.001. [PubMed][Cross Ref]

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